Echinococcus hydatid

The photo on the top is an overview of a section through a unilocular hydatid cyst within liver tissue. There is a large lumen surrounded by a thick laminated layer, with a thin band of host tissue is visible around it. In the lumen is a section through part of a brood capsule.

The photo on the bottom is a close-up of the wall of the hydatid, showing many of its layers. At the left of the photo is the thick laminated layer. It is highly wrinkled and has pulled away from overlying layers somewhat because it is very fibrous and distorts easily during histological preparation. This laminated layer is the outermost layer of the cyst and is of parasite origin. Outside the laminated layer (above and to the right) are layers of host cells. The thin, dense band of darkly-staining cells is an accumulation of host inflammatory cells that had gathered next to the laminated layer. Outside that are two bands of host tissue, largely composed of fibroblasts laying down a dense capsule of connective tissue. This walls off the parasite and actually reduces the antigenicity of the parasite.