• B.Sc.: McMaster University (1989)
• M.Sc., York University, Supervisor M. Barrie Coukell (1993)
• Ph.D., Simon Fraser University, Supervisor Charles M. Boone (Boone Lab) (1997)
• P.D.F., Washington University School of Medicine, Supervisor John A. Cooper (Cooper Lab) (1997)
  
  
  

My area of interest is the regulation of cell division. I am currently studying:

1) a cell cycle checkpoint that acts late in mitosis

2) the mechanisms underlying nuclear migration and spindle positioning. The cell cycle checkpoint, called the "spindle position checkpoint", responds to mispositioned spindles and delays exit from mitosis until the spindle position is corrected.

I am using a variety of approaches to study these processes, primarily molecular genetics and cell biology. The budding yeast Saccharomyces cerevisiae has been useful for identifying proteins involved in the spindle position checkpoint and in nuclear migration/spindle positioning. I am continuing my work in budding yeast and will be applying what I learn to cultured vertebrate cells to determine if the mechanisms controlling spindle position and exit from mitosis are conserved.

 

• Microscopy Unit Committee
• Microbiology and Biotechnology Research Interest Group
• Molecular Biology and Genetics Research Interest Group
• Molecular Genetics, Canada Research Chair

• Genetics 301
• Genetics 304
• Genetics 510