Morphological forms of Trypanosoma cruzi

(Redrawn after Baker 1969)

The amastigote is intracellular in host muscles, and has a short flagellum that does not protrude. Promastigotes are intermediary forms during multiplication of amastigotes, and may be seen in interstitial spaces nearby. The kinetoplast is anterior to the nucleus and there is a free flagellum but no undulating membrane. The epimastigote occurs within the insect vector. The kinetoplast is anterior to the nucleus and there is a free flagellum, but there is also an undulating membrane. The trypomastigote is found circulating in the vertebrate host's blood. It has a kinetoplast at the posterior end of the body, a flagellum which travels anteriorly past the nucleus, and also possesses an undulating membrane. The trypomastigote of this species is often "C"-shaped when fixed.